Lobular breast cancer: incidence and genetic and non-genetic risk factors
نویسندگان
چکیده
منابع مشابه
Genetic polymorphism in ERCC5 and breast cancer risk
ERCC5 plays crucial role in excision repair DNA damage induced by UV in NER pathway. Single neuleotide polymorphism in ERCC5 were responsible for different cancers.Therefore, current study evaluated the relationship between ERCC5 (rs1047768 T>C) polymorphism and the risk of breast cancer in Pakistani population. The rs1047768 polymorphism was screened among 175 female...
متن کاملGenetic polymorphism in ERCC5 and breast cancer risk
ERCC5 plays crucial role in excision repair DNA damage induced by UV in NER pathway. Single neuleotide polymorphism in ERCC5 were responsible for different cancers.Therefore, current study evaluated the relationship between ERCC5 (rs1047768 T>C) polymorphism and the risk of breast cancer in Pakistani population. The rs1047768 polymorphism was screened among 175 female...
متن کاملDissecting genetic risk factors in breast cancer
Breast cancer associated with germline pathogenic variants in BRCA1 or BRCA2 is recognized for its strong familial risk [1]. In addition to these BRCA1 and BRCA2 variants, other rare (allele frequency < 0.005) highly penetrant variants in TP53, PTEN, and ATM account for ~25% of breast cancer familial risk [2]. Other susceptibility genes have been identified (PALB2, CHEK2, RECQL, NBN) as well as...
متن کاملBreast Cancer: Risk Factors, Diagnosis and Management
ABSTRACT Breast cancer remains the most common cancer of women and one of the most common causes of cancer-related deaths worldwide. In spite of major advances in breast cancer diagnosis and treatment, the incidence of breast cancer remains high and the treatment of metastatic breast cancer remains challenging. This review presents an over...
متن کاملBreast Cancer Overview: Risk Factors, Screening, Genetic Testing, and Prevention
Breast cancer is the most common malignancy in women, accounting for 27% of all female cancers; it accounts for < 1% of all cancer cases in men. Breast cancer also is responsible for 15% of cancer deaths in women, making it the number-two cause of cancer death. An estimated 207,090 new breast cancer cases will be diagnosed in women and 1,970 new cases will be diagnosed in men in the United Stat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2015
ISSN: 1465-542X
DOI: 10.1186/s13058-015-0546-7